Gel Electrophoresis Reagents and Buffers
Bio Rad Laboratories AMPLISIZE MOLECULAR RULER
Criterion Tris-HCl gels are precast polyacrylamide gels for vertical SDS-PAGE and native PAGE protein separations. Gels 13.3 cm x 8.7 cm x 1.0 mm (W x L x thickness) are supplied in a 15.0 x 10.6 cm cassette and are compatible with Criterio.
ABclonal Technology BAG3 Rabbit pAb
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Quality Biological Inc TBS 10X pH 7.4, 500 mL
TBS 10X pH 7.4 is used as a washing buffer for cellular and molecular biology techniques. ¿ DNase, RNase and Protease tested. ¿ Applications: TBS 10X pH 7.4 will be useful as a washing buffer for electrodes, microtiter plates, and alkaline phophatase or peroxidase conjugates. TBS 10X pH 7.4 can also be used in detergent preparation and Western blot or ELISA applications. ¿ Storage Conditions: 15¿C to 30¿C ¿ Shipping Condition: ambient temperature ¿ Sterile Filtered ¿ DNase, RNase, and Protease Tested ¿ pH: 7.4¿0.1 ¿ Product and/or packaging contains recycled/renewable content ¿ Product and/or packaging is recyclable or reduces waste ¿ Product and/or packaging is safer to human and environmental health ¿ ¿ Max Shelf Life: 36 months
ABclonal Technology JARID2 Rabbit mAb
This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies.
ABclonal Technology SMPD3 Rabbit pAb
Predicted to enable phosphatidic acid binding activity, phosphatidylserine binding activity, and sphingomyelin phosphodiesterase activity. Predicted to be involved in positive regulation of exosomal secretion and sphingomyelin metabolic process. Predicted to act upstream of or within several processes, including animal organ development, enzyme linked receptor protein signaling pathway, and sphingolipid metabolic process. Predicted to be located in Golgi apparatus and plasma membrane. Predicted to be active in cytoplasm. Biomarker of pulmonary emphysema.
ABclonal Technology GSK3α Rabbit pAb
This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimers disease.
ABclonal Technology ZSCAN4C Rabbit pAb
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within negative regulation of mitotic recombination, regulation of transcription by RNA polymerase II, and telomere maintenance via telomere lengthening. Located in chromosome, telomeric region, cytoplasm, and nucleus. Is expressed in 1-cell stage embryo, 2-cell stage embryo, primary oocyte, and secondary oocyte. Orthologous to human ZSCAN4 (zinc finger and SCAN domain containing 4).
Abcam Bisbenzimide H 33258 (Hoechst 33258), adenine-thymine selective DNA fluorescent stain, 100MG
MW 533.9 Da, Purity >98%. Cell-permeable, adenine-thymine selective DNA fluorescent stain. DNA minor groove-directed agent. Labels DNA, chromosomes and nuclei. Stimulates topoisomerase I-mediated DNA cleavage. Bisbenzimide H 33342 (ab145596) analog.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical VItelogenInsalmon Monclo 500uL
A selective brain-penetrable LRRK2 inhibitor (Ki 0.7 nM) inhibits LRRK2 Ser1292 autophosphorylation in BAC transgenic mice expressing human LRRK2 protein with the G2019S Parkinsons disease mutation (IC50 3 nM in vivo)
ABclonal Technology KIF4A Rabbit mAb
This gene encodes a member of the kinesin 4 subfamily of kinesin related proteins. The encoded protein is an ATP dependent microtubule-based motor protein that is involved in the intracellular transport of membranous organelles. This protein also associates with condensed chromosome arms and may be involved in maintaining chromosome integrity during mitosis. This protein may also be involved in the organization of the central spindle prior to cytokinesis. A pseudogene of this gene is found on chromosome X.